USING BAYESIAN METHODS IN THE TASK OF MODELING THE PATIENTS' PHARMACORESISTANCE DEVELOPMENT

Main Article Content

Saule S. Smailova

Saule_Smailova@mail.ru

Luidmila N. Lytvynenko

llytvynenko58@gmail.com

Nataliia B. Savina

n.b.savina@nuwm.edu.ua

Volodymyr I. Lytvynenko

immun56@gmail.com

Abstract

In this paper, we propose a methodology for using static Bayesian networks (BN) in modeling the development of pharmacoresistance in patients with a diagnosis of epilepsy. Methods for constructing the structure of a static BN, their parametric training, validation, sensitivity analysis and “What-if” scenario analysis are considered. The model was designed in collaboration with expert doctors, as well as expert pharmacologists in the selection and quantification of input and output variables.

Keywords:

epileptology, pharmacoresistance, Bayesian networks, structural learning, parametric learning, sensitivity analysis, validation

References

Article Details

USING BAYESIAN METHODS IN THE TASK OF MODELING THE PATIENTS’ PHARMACORESISTANCE DEVELOPMENT. (2022). Informatyka, Automatyka, Pomiary W Gospodarce I Ochronie Środowiska, 12(2), 77-82. https://doi.org/10.35784/iapgos.2968