EYE-TRACKING IN DIAGNOSIS OF NEURODEGENERATIVE DISEASE


Abstract

Eye-tracking allows for non-invasive examination and the same eyetrackers are becoming more available, thus its popularity in medical diagnosis and other fields of application is increasing. The paper presents the possibilities for using eye-tracking in the diagnosis neurodegenerative disease such as Parkinson or Alzheimer diseases. The autor describes the exetracking experiment, the model of fixations and saccedes detection, as well as the selected examples of eye-tracking research conducted among patients with neurodegenerative diseases.


Keywords

eye tracking; biomedical signal processing; computer aided diagnosis

Anderson T.J., MacAskill M.R.: Eye movements in patients with neurodegenerative disorders. Nature Reviews Neurology, 9(2), 2013, 74-85.

Duchowski, A.: Eye tracking methodology: Theory and practice, Vol. 373, Springer Science & Business Media, 2007.

Garbutt S., Matlin A., Hellmuth J., Schenk A.K., Johnson J.K., Rosen H., Boxer A.L.: Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease. Brain, 131(5), 2008, 1268-1281.

Holmqvist K., Nyström M., Andersson R., Dewhurst R., Jarodzka H, Van de Weijer J.: Eye tracking: A comprehensive guide to methods and measures. Oxford University Press, 2011.

Jadanowski K., Budrewicz S., Koziorowska-Gawron E.: Zaburzenia gałkoruchowe w chorobach ośrodkowego układu nerwowego. Polski Przegląd Neurologiczny, 6(4), 2010, 202-211.

Komogortsev O.V., Gobert D.V., Jayarathna S., Koh D.H., Gowda S.M.: Standardization of automated analyses of oculomotor fixation and saccadic behaviors. Biomedical Engineering, IEEE Transactions, 57(11), 2010, 2635-2645.

Komogortsev O.V., Jayarathna, S., Koh D.H., Gowda S.M.: Qualitative and quantitative scoring and evaluation of the eye movement classification algorithms. Proceedings of the 2010 Symposium on Eye-Tracking Research & Applications ACM, 2010, 65-68.

Komogortsev O.V., Khan J.I.: Kalman filtering in the design of eye-gaze-guided computer interfaces. Human-Computer Interaction. HCI Intelligent Multimodal Interaction Environments, Springer Berlin Heidelberg, 2007, 679-689.

Kuechenmeister C.A., Linton P. H., Mueller T.V., White H.B.: Eye Tracking in Relation to Age, Sex, and Illness. Arch Gen Psychiatry, 34(5), 1977, 578-579.

Mosimann U.P., Müri R.M., Burn D.J., Felblinger J., O'Brien J.T., McKeith I.G.: Saccadic eye movement changes in Parkinson's disease dementia and dementia with Lewy bodies. Brain, 128(6), 2005, 1267-1276.

Ober J., Dylak J., Gryncewicz W., Przedpelska-Ober E.: Sakkadometria–nowe możliwości oceny stanu czynnościowego ośrodkowego układu nerwowego. [Saccadometryp-new possibilities of evaluating the state of the central nervous system activity]. Nauka, 4, 2009, 109-135.

Peltsch, A., Hoffman, A., Armstrong, I., Pari, G., Munoz, D.P.: Saccadic impairments in Huntington’s disease. Experimental brain research, 186(3), 2008, 457-469.

Salvucci D.D., Goldberg J.H.: Identifying fixations and saccades in eye-tracking protocols. Proceedings of the 2000 symposium on Eye tracking research & applications. ACM, 2000, 71-78.

Sauter D., Martin B.J., Di Renzo N., Vomscheid C.: Analysis of eye tracking movements using innovations generated by a Kalman filter. Medical and biological Engineering and Computing, 29(1), 1991, 63-69.

Terao Y., Fukuda H., Yugeta A., Hikosaka O., Nomura Y., Segawa M., Ugawa Y.: Initiation and inhibitory control of saccades with the progression of Parkinson's disease–changes in three major drives converging on the superior colliculus. Neuropsychologia, 49(7), 2011, 1794-1806.

Verheij S., Muilwijk D., Pel J.J., van der Cammen T.J., Mattace-Raso F.U., van der Steen J.: Visuomotor impairment in early-stage Alzheimer's disease: changes in relative timing of eye and hand movements. Journal of Alzheimer's Disease, 30(1), 2012, 131-143.


Published : 2015-06-30


Borys, M. (2015). EYE-TRACKING IN DIAGNOSIS OF NEURODEGENERATIVE DISEASE. Informatyka, Automatyka, Pomiary W Gospodarce I Ochronie Środowiska, 5(2), 55-63. https://doi.org/10.5604/20830157.1159331

Magdalena Borys  m.borys@pollub.pl
Politechnika Lubelska, Instytut Informatyki  Poland