THE SYSTEM FOR COMPLEX MAGNETIC SUSCEPTIBILITY MEASUREMENT OF NANOPARTICLES WITH 3D PRINTED CARCASS FOR INTEGRATED RECEIVE COILS

Mateusz Midura

mmidura@ire.pw.edu.pl
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-2449-0652

Przemysław Wróblewski


Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-6713-9088

Damian Wanta


Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-1596-6524

Grzegorz Domański


Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-0204-2322

Mateusz Stosio


Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-7488-1969

Jacek Kryszyn


Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-0042-0473

Waldemar T. Smolik


Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-1524-5049

Abstract

The article concerns the research on the properties of core-shell superparamagnetic nanoparticles in the context of their use in medicine for diagnostics and therapy. The article presents a system for impedance (AC) spectroscopy of nanoparticles with a new arrangement of receive coils. A significant modification was the position of the reference coil in relation to the receive coils as well as the method of winding and routing the wires on the carcass. The 3D printing technique was used in the production of the measuring coil system. The aim of the work was to experimentally verify the developed measurement system and analyze its properties. The system tests were carried out at low frequencies ranging from 2 to 50 kHz. Complex magnetic susceptibility was measured for superparamagnetic iron oxide nanoparticles in polymer shells in a physiological saline solution. The obtained results confirmed the relevance of the concept of the measurements. In summary, the observed properties of the realized system are discussed and further directions of its development are proposed.


Keywords:

superparamagnetic nanoparticles, magnetic particle spectroscopy, magnetic susceptibility, hyperthermia

Bogren S. et al.: Classification of Magnetic Nanoparticle Systems–Synthesis, Standardization and Analysis Methods in the NanoMag Project. International Journal of Molecular Sciences 16(9)/2015, 20308–20325 [http://doi.org/10.3390/ijms160920308].
DOI: https://doi.org/10.3390/ijms160920308   Google Scholar

Graeser M. et al.: Analog receive signal processing for magnetic particle imaging. Med. Phys. 40(4)/2013, 042303 [http://doi.org/10.1118/1.4794482].
DOI: https://doi.org/10.1118/1.4794482   Google Scholar

Harabech M. et al.: The Effect of the Magnetic Nanoparticle’s Size Dependence of the Relaxation Time Constant on the Specific Loss Power of Magnetic Nanoparticle Hyperthermia. Journal of Magnetism and Magnetic Materials 426/2017, 206–210 [http://doi.org/10.1016/j.jmmm.2016.11.079].
DOI: https://doi.org/10.1016/j.jmmm.2016.11.079   Google Scholar

Hergt R. et al.: Magnetic Particle Hyperthermia: Nanoparticle Magnetism and Materials Development for Cancer Therapy. Journal of Physics Condensed Matter 18(38)/2006, S2919 [http://doi.org/10.1088/0953-8984/18/38/S26].
DOI: https://doi.org/10.1088/0953-8984/18/38/S26   Google Scholar

Kishore K., Akbar S. A.: Evolution of Lock-In Amplifier as Portable Sensor Interface Platform: A Review. IEEE Sensors Journal 20(18)/2020, 10345–10354 [http://doi.org/10.1109/JSEN.2020.2993309].
DOI: https://doi.org/10.1109/JSEN.2020.2993309   Google Scholar

Ludwig F. et al.: Analysis of AC Susceptibility Spectra for the Characterization of Magnetic Nanoparticles. IEEE Transactions on Magnetics 53(11)/2017, 10–13 [http://doi.org/10.1109/TMAG.2017.2693420].
DOI: https://doi.org/10.1109/TMAG.2017.2693420   Google Scholar

Mahdavi Z. et al.: Core-Shell Nanoparticles Used in Drug Delivery-Microfluidics: A Review. RSC Advances 10(31)/2020, 18280–18295 [http://doi.org/10.1039/d0ra01032d].
DOI: https://doi.org/10.1039/D0RA01032D   Google Scholar

Maity D., Ganeshlenin K.: Superparamagnetic Nanoparticles for Cancer Hyperthermia Treatment. Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy, Springer Berlin Heidelberg, 2019, 299–332 [http://doi.org/10.1007/978-3-662-59596-1_7].
DOI: https://doi.org/10.1007/978-3-662-59596-1_7   Google Scholar

Reeves D. B., Weaver J. B.: Magnetic Nanoparticle Sensing: Decoupling the Magnetization from the Excitation Field. Journal of Physics D: Applied Physics 47(4)/2013, 45002 [http://doi.org/10.1088/0022-3727/47/4/045002].
DOI: https://doi.org/10.1088/0022-3727/47/4/045002   Google Scholar

Sandler S. E. et al.: Best Practices for Characterization of Magnetic Nanoparticles for Biomedical Applications. Analytical Chemistry 91(22)/2019, 14159–14169 [http://doi.org/10.1021/acs.analchem.9b03518].
DOI: https://doi.org/10.1021/acs.analchem.9b03518   Google Scholar

Šouc J. et al.: Calibration Free Method for Measurement of the AC Magnetization Loss. Superconductor Science and Technology 18(5)/2005, 592–595 [http://doi.org/10.1088/0953-2048/18/5/003].
DOI: https://doi.org/10.1088/0953-2048/18/5/003   Google Scholar

Suhaimi N. S. et al.: A Resonant Type AC Magnetometer for Evaluation of Magnetic Nanoparticles. Hassan M. (eds) Intelligent Manufacturing & Mechatronics. Lecture Notes in Mechanical Engineering. Springer, Singapore 2018 [http://doi.org/10.1007/978-981-10-8788-2_9].
DOI: https://doi.org/10.1007/978-981-10-8788-2_9   Google Scholar

Sun Y. et al.: An Improved Method for Estimating Core Size Distributions of Magnetic Nanoparticles via Magnetization Harmonics. Nanomaterials 10(9)/2020, 1–12 [http://doi.org/10.3390/nano10091623].
DOI: https://doi.org/10.3390/nano10091623   Google Scholar

Valentini M. et al.: Diffusion NMR Spectroscopy for the Characterization of the Size and Interactions of Colloidal Matter: The Case of Vesicles and Nanoparticles. Journal of the American Chemical Society 126(7)/2004, 2142–2147 [http://doi.org/10.1021/ja037247r].
DOI: https://doi.org/10.1021/ja037247r   Google Scholar

Vallejo-Fernandez G. et al.: Mechanisms of Hyperthermia in Magnetic Nanoparticles. Journal of Physics D: Applied Physics 46(31)/2013 [http://doi.org/10.1088/0022-3727/46/31/312001].
DOI: https://doi.org/10.1088/0022-3727/46/31/312001   Google Scholar

Van De Loosdrecht M. M. et al.: A Novel Characterization Technique for Superparamagnetic Iron Oxide Nanoparticles: The Superparamagnetic Quantifier, Compared with Magnetic Particle Spectroscopy. Review of Scientific Instruments 90(2)/2019 [http://doi.org/10.1063/1.5039150].
DOI: https://doi.org/10.1063/1.5039150   Google Scholar

Wróblewski P., Smolik W.: Coil design with litze wire for magnetic particle spectrometry. Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska 7(1)/2017, 150–153 [http://doi.org/10.5604/01.3001.0010.4605].
DOI: https://doi.org/10.5604/01.3001.0010.4605   Google Scholar

Wu K. et al.: Magnetic Particle Spectroscopy: A Short Review of Applications Using Magnetic Nanoparticles. ACS Applied Nano Materials 3(6)/2020, 4972–89 [http://doi.org/10.1021/acsanm.0c00890].
DOI: https://doi.org/10.1021/acsanm.0c00890   Google Scholar

Yang T. Q. et al.: Detection of Magnetic Nanoparticles with Ac Susceptibility Measurement. Physica C: Superconductivity and Its Applications 412–414/2004, 1496–1500 [http://doi.org/10.1016/j.physc.2004.01.146].
DOI: https://doi.org/10.1016/j.physc.2004.01.146   Google Scholar

Quantum Design, MPMS Application Note 1070-207: Using PPMS Superconducting Magnets at Low Fields 2009.
  Google Scholar

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Published
2021-03-31

Cited by

Midura, M., Wróblewski, P., Wanta, D., Domański, G., Stosio, M., Kryszyn, J., & Smolik, W. T. (2021). THE SYSTEM FOR COMPLEX MAGNETIC SUSCEPTIBILITY MEASUREMENT OF NANOPARTICLES WITH 3D PRINTED CARCASS FOR INTEGRATED RECEIVE COILS. Informatyka, Automatyka, Pomiary W Gospodarce I Ochronie Środowiska, 11(1), 4–9. https://doi.org/10.35784/iapgos.2456

Authors

Mateusz Midura 
mmidura@ire.pw.edu.pl
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-2449-0652

Authors

Przemysław Wróblewski 

Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-6713-9088

Authors

Damian Wanta 

Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-1596-6524

Authors

Grzegorz Domański 

Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-0204-2322

Authors

Mateusz Stosio 

Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-7488-1969

Authors

Jacek Kryszyn 

Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-0042-0473

Authors

Waldemar T. Smolik 

Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-1524-5049

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