THE SYSTEM FOR COMPLEX MAGNETIC SUSCEPTIBILITY MEASUREMENT OF NANOPARTICLES WITH 3D PRINTED CARCASS FOR INTEGRATED RECEIVE COILS
Mateusz Midura
mmidura@ire.pw.edu.plWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-2449-0652
Przemysław Wróblewski
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-6713-9088
Damian Wanta
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-1596-6524
Grzegorz Domański
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-0204-2322
Mateusz Stosio
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-7488-1969
Jacek Kryszyn
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-0042-0473
Waldemar T. Smolik
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics (Poland)
https://orcid.org/0000-0002-1524-5049
Abstract
The article concerns the research on the properties of core-shell superparamagnetic nanoparticles in the context of their use in medicine for diagnostics and therapy. The article presents a system for impedance (AC) spectroscopy of nanoparticles with a new arrangement of receive coils. A significant modification was the position of the reference coil in relation to the receive coils as well as the method of winding and routing the wires on the carcass. The 3D printing technique was used in the production of the measuring coil system. The aim of the work was to experimentally verify the developed measurement system and analyze its properties. The system tests were carried out at low frequencies ranging from 2 to 50 kHz. Complex magnetic susceptibility was measured for superparamagnetic iron oxide nanoparticles in polymer shells in a physiological saline solution. The obtained results confirmed the relevance of the concept of the measurements. In summary, the observed properties of the realized system are discussed and further directions of its development are proposed.
Keywords:
superparamagnetic nanoparticles, magnetic particle spectroscopy, magnetic susceptibility, hyperthermiaReferences
Bogren S. et al.: Classification of Magnetic Nanoparticle Systems–Synthesis, Standardization and Analysis Methods in the NanoMag Project. International Journal of Molecular Sciences 16(9)/2015, 20308–20325 [http://doi.org/10.3390/ijms160920308].
DOI: https://doi.org/10.3390/ijms160920308
Google Scholar
Graeser M. et al.: Analog receive signal processing for magnetic particle imaging. Med. Phys. 40(4)/2013, 042303 [http://doi.org/10.1118/1.4794482].
DOI: https://doi.org/10.1118/1.4794482
Google Scholar
Harabech M. et al.: The Effect of the Magnetic Nanoparticle’s Size Dependence of the Relaxation Time Constant on the Specific Loss Power of Magnetic Nanoparticle Hyperthermia. Journal of Magnetism and Magnetic Materials 426/2017, 206–210 [http://doi.org/10.1016/j.jmmm.2016.11.079].
DOI: https://doi.org/10.1016/j.jmmm.2016.11.079
Google Scholar
Hergt R. et al.: Magnetic Particle Hyperthermia: Nanoparticle Magnetism and Materials Development for Cancer Therapy. Journal of Physics Condensed Matter 18(38)/2006, S2919 [http://doi.org/10.1088/0953-8984/18/38/S26].
DOI: https://doi.org/10.1088/0953-8984/18/38/S26
Google Scholar
Kishore K., Akbar S. A.: Evolution of Lock-In Amplifier as Portable Sensor Interface Platform: A Review. IEEE Sensors Journal 20(18)/2020, 10345–10354 [http://doi.org/10.1109/JSEN.2020.2993309].
DOI: https://doi.org/10.1109/JSEN.2020.2993309
Google Scholar
Ludwig F. et al.: Analysis of AC Susceptibility Spectra for the Characterization of Magnetic Nanoparticles. IEEE Transactions on Magnetics 53(11)/2017, 10–13 [http://doi.org/10.1109/TMAG.2017.2693420].
DOI: https://doi.org/10.1109/TMAG.2017.2693420
Google Scholar
Mahdavi Z. et al.: Core-Shell Nanoparticles Used in Drug Delivery-Microfluidics: A Review. RSC Advances 10(31)/2020, 18280–18295 [http://doi.org/10.1039/d0ra01032d].
DOI: https://doi.org/10.1039/D0RA01032D
Google Scholar
Maity D., Ganeshlenin K.: Superparamagnetic Nanoparticles for Cancer Hyperthermia Treatment. Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy, Springer Berlin Heidelberg, 2019, 299–332 [http://doi.org/10.1007/978-3-662-59596-1_7].
DOI: https://doi.org/10.1007/978-3-662-59596-1_7
Google Scholar
Reeves D. B., Weaver J. B.: Magnetic Nanoparticle Sensing: Decoupling the Magnetization from the Excitation Field. Journal of Physics D: Applied Physics 47(4)/2013, 45002 [http://doi.org/10.1088/0022-3727/47/4/045002].
DOI: https://doi.org/10.1088/0022-3727/47/4/045002
Google Scholar
Sandler S. E. et al.: Best Practices for Characterization of Magnetic Nanoparticles for Biomedical Applications. Analytical Chemistry 91(22)/2019, 14159–14169 [http://doi.org/10.1021/acs.analchem.9b03518].
DOI: https://doi.org/10.1021/acs.analchem.9b03518
Google Scholar
Šouc J. et al.: Calibration Free Method for Measurement of the AC Magnetization Loss. Superconductor Science and Technology 18(5)/2005, 592–595 [http://doi.org/10.1088/0953-2048/18/5/003].
DOI: https://doi.org/10.1088/0953-2048/18/5/003
Google Scholar
Suhaimi N. S. et al.: A Resonant Type AC Magnetometer for Evaluation of Magnetic Nanoparticles. Hassan M. (eds) Intelligent Manufacturing & Mechatronics. Lecture Notes in Mechanical Engineering. Springer, Singapore 2018 [http://doi.org/10.1007/978-981-10-8788-2_9].
DOI: https://doi.org/10.1007/978-981-10-8788-2_9
Google Scholar
Sun Y. et al.: An Improved Method for Estimating Core Size Distributions of Magnetic Nanoparticles via Magnetization Harmonics. Nanomaterials 10(9)/2020, 1–12 [http://doi.org/10.3390/nano10091623].
DOI: https://doi.org/10.3390/nano10091623
Google Scholar
Valentini M. et al.: Diffusion NMR Spectroscopy for the Characterization of the Size and Interactions of Colloidal Matter: The Case of Vesicles and Nanoparticles. Journal of the American Chemical Society 126(7)/2004, 2142–2147 [http://doi.org/10.1021/ja037247r].
DOI: https://doi.org/10.1021/ja037247r
Google Scholar
Vallejo-Fernandez G. et al.: Mechanisms of Hyperthermia in Magnetic Nanoparticles. Journal of Physics D: Applied Physics 46(31)/2013 [http://doi.org/10.1088/0022-3727/46/31/312001].
DOI: https://doi.org/10.1088/0022-3727/46/31/312001
Google Scholar
Van De Loosdrecht M. M. et al.: A Novel Characterization Technique for Superparamagnetic Iron Oxide Nanoparticles: The Superparamagnetic Quantifier, Compared with Magnetic Particle Spectroscopy. Review of Scientific Instruments 90(2)/2019 [http://doi.org/10.1063/1.5039150].
DOI: https://doi.org/10.1063/1.5039150
Google Scholar
Wróblewski P., Smolik W.: Coil design with litze wire for magnetic particle spectrometry. Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska 7(1)/2017, 150–153 [http://doi.org/10.5604/01.3001.0010.4605].
DOI: https://doi.org/10.5604/01.3001.0010.4605
Google Scholar
Wu K. et al.: Magnetic Particle Spectroscopy: A Short Review of Applications Using Magnetic Nanoparticles. ACS Applied Nano Materials 3(6)/2020, 4972–89 [http://doi.org/10.1021/acsanm.0c00890].
DOI: https://doi.org/10.1021/acsanm.0c00890
Google Scholar
Yang T. Q. et al.: Detection of Magnetic Nanoparticles with Ac Susceptibility Measurement. Physica C: Superconductivity and Its Applications 412–414/2004, 1496–1500 [http://doi.org/10.1016/j.physc.2004.01.146].
DOI: https://doi.org/10.1016/j.physc.2004.01.146
Google Scholar
Quantum Design, MPMS Application Note 1070-207: Using PPMS Superconducting Magnets at Low Fields 2009.
Google Scholar
Authors
Mateusz Midurammidura@ire.pw.edu.pl
Warsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-2449-0652
Authors
Przemysław WróblewskiWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-6713-9088
Authors
Damian WantaWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-1596-6524
Authors
Grzegorz DomańskiWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-0204-2322
Authors
Mateusz StosioWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-7488-1969
Authors
Jacek KryszynWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-0042-0473
Authors
Waldemar T. SmolikWarsaw University of Technology, Faculty of Electronics and Information Technology, Institute of Radioelectronics and Multimedia Technology, Division of Medical and Nuclear Electronics Poland
https://orcid.org/0000-0002-1524-5049
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