CARDIOMETABOLIC RISK PREDICTION IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE COMBINED WITH SUBCLINICAL HYPOTHYROIDISM
Olena Kolesnikova
kolesnikova1973@gmail.comGovernment Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0001-5606-6621
Olena Vysotska
National Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0003-3723-9771
Anna Potapenko
Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0002-1658-0156
Anastasia Radchenko
Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0002-9687-8218
Anna Trunova
National Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0001-7069-0674
Natalia Virstyuk
Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine (Ukraine)
http://orcid.org/0000-0002-5794-8754
Liudmyla Vasylevska-Skupa
Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine (Ukraine)
http://orcid.org/0000-0002-1989-7175
Aliya Kalizhanova
Institute of Information and Computational Technologies, Almaty, Kazakhstan (Kazakhstan)
http://orcid.org/0000-0002-5979-9756
Nazerka Mukanova
Gymnasium No. 159 named after Y. Altynsarin, Almaty, Kazakhstan (Kazakhstan)
http://orcid.org/0009-0002-7945-7187
Abstract
One of the most common diseases of our time is non-alcoholic fatty liver disease (NAFLD). Recently published research results indicate that patients with NAFLD along with traditional risk factors for cardiovascular diseases (CVD) have "new" risk factors such as endothelial dysfunction (ED), carotid intima-media thickness (CIMT), an increase in the CRP level, as well as risk factors combined into the Framingham scale. It is also known that combination of NAFLD with subclinical hypothyroidism (SH) forms an abnormal metabolic phenotype, which is associated with cardiometabolic risk factors. The study of cardiometabolic predictors and vascular markers in patients with NAFLD in combination with SH will provide an opportunity to improve the strategy of cardiovascular events prevention in such comorbid patients.
Keywords:
cardiometabolic risk, non-alcoholic fatty liver disease, subclinical hypothyroidism, prediction, binary regression logistic analysis, validation of prognostic modelsReferences
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Authors
Olena Kolesnikovakolesnikova1973@gmail.com
Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0001-5606-6621
Authors
Olena VysotskaNational Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0003-3723-9771
Authors
Anna PotapenkoGovernment Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0002-1658-0156
Authors
Anastasia RadchenkoGovernment Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0002-9687-8218
Authors
Anna TrunovaNational Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0001-7069-0674
Authors
Natalia VirstyukIvano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine Ukraine
http://orcid.org/0000-0002-5794-8754
Authors
Liudmyla Vasylevska-SkupaIvano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine Ukraine
http://orcid.org/0000-0002-1989-7175
Authors
Aliya KalizhanovaInstitute of Information and Computational Technologies, Almaty, Kazakhstan Kazakhstan
http://orcid.org/0000-0002-5979-9756
Authors
Nazerka MukanovaGymnasium No. 159 named after Y. Altynsarin, Almaty, Kazakhstan Kazakhstan
http://orcid.org/0009-0002-7945-7187
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