CARDIOMETABOLIC RISK PREDICTION IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE COMBINED WITH SUBCLINICAL HYPOTHYROIDISM

Olena Kolesnikova

kolesnikova1973@gmail.com
Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0001-5606-6621

Olena Vysotska


National Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0003-3723-9771

Anna Potapenko


Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0002-1658-0156

Anastasia Radchenko


Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0002-9687-8218

Anna Trunova


National Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine (Ukraine)
http://orcid.org/0000-0001-7069-0674

Natalia Virstyuk


Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine (Ukraine)
http://orcid.org/0000-0002-5794-8754

Liudmyla Vasylevska-Skupa


Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine (Ukraine)
http://orcid.org/0000-0002-1989-7175

Aliya Kalizhanova


Institute of Information and Computational Technologies, Almaty, Kazakhstan (Kazakhstan)
http://orcid.org/0000-0002-5979-9756

Nazerka Mukanova


Gymnasium No. 159 named after Y. Altynsarin, Almaty, Kazakhstan (Kazakhstan)
http://orcid.org/0009-0002-7945-7187

Abstract

One of the most common diseases of our time is non-alcoholic fatty liver disease (NAFLD). Recently published research results indicate that patients with NAFLD along with traditional risk factors for cardiovascular diseases (CVD) have "new" risk factors such as endothelial dysfunction (ED), carotid intima-media thickness (CIMT), an increase in the CRP level, as well as risk factors combined into the Framingham scale. It is also known that combination of NAFLD with subclinical hypothyroidism (SH) forms an abnormal metabolic phenotype, which is associated with cardiometabolic risk factors. The study of cardiometabolic predictors and vascular markers in patients with NAFLD in combination with SH will provide an opportunity to improve the strategy of cardiovascular events prevention in such comorbid patients.


Keywords:

cardiometabolic risk, non-alcoholic fatty liver disease, subclinical hypothyroidism, prediction, binary regression logistic analysis, validation of prognostic models

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Published
2023-06-30

Cited by

Kolesnikova, O., Vysotska, O., Potapenko, A., Radchenko, A., Trunova, A., Virstyuk, N., … Mukanova, N. (2023). CARDIOMETABOLIC RISK PREDICTION IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE COMBINED WITH SUBCLINICAL HYPOTHYROIDISM. Informatyka, Automatyka, Pomiary W Gospodarce I Ochronie Środowiska, 13(2), 64–68. https://doi.org/10.35784/iapgos.3654

Authors

Olena Kolesnikova 
kolesnikova1973@gmail.com
Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0001-5606-6621

Authors

Olena Vysotska 

National Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0003-3723-9771

Authors

Anna Potapenko 

Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0002-1658-0156

Authors

Anastasia Radchenko 

Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0002-9687-8218

Authors

Anna Trunova 

National Aerospace University "Kharkiv Aviation Institute", Kharkiv, Ukraine Ukraine
http://orcid.org/0000-0001-7069-0674

Authors

Natalia Virstyuk 

Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine Ukraine
http://orcid.org/0000-0002-5794-8754

Authors

Liudmyla Vasylevska-Skupa 

Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine Ukraine
http://orcid.org/0000-0002-1989-7175

Authors

Aliya Kalizhanova 

Institute of Information and Computational Technologies, Almaty, Kazakhstan Kazakhstan
http://orcid.org/0000-0002-5979-9756

Authors

Nazerka Mukanova 

Gymnasium No. 159 named after Y. Altynsarin, Almaty, Kazakhstan Kazakhstan
http://orcid.org/0009-0002-7945-7187

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